Tretinoin

Tretinoin skin preparations are a family of drugs all similar to Vitamin A. In general, tretinoin gels are stronger than tretinoin creams because the medicine penetrates better when in a gel form. Tretinoin is used to treat acne and aged, sun damaged skin. Tretinoin works best when used in combination with alpha hydroxyacid preparations. If used over a period of years, tretinoin will continue to reverse aging of the skin and can continue improving the skin’s appearance even ten years after starting treatment.

Tretinoin comes in topical liquid, cream, and gel. Tretinoin usually is used daily at bedtime or once every 2 or 3 days. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use tretinoin exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Your acne probably will get worse (red, scaling skin and an increase in acne sores) during the first 7-10 days that you use this medication. Nevertheless, continue to use it; the acne sores should disappear. Usually 2-3 weeks (and sometimes more than 6 weeks) of regular use of tretinoin is required before improvement is seen.

Use only nonmedicated cosmetics on cleansed skin. Do not use topical preparations with a lot of alcohol, menthol, spices, or lime (e.g., shaving lotions, astringents, and perfumes); they can sting your skin, especially when you first use tretinoin.

Do not use any other topical medications, especially benzoyl peroxide, salicylic acid (wart remover), and dandruff shampoos containing sulfur or resorcinol unless your doctor directs you to do so. If you have used any of these topical medications recently, ask your doctor if you should wait before using tretinoin.

Most common brands of tretinoin are Retin-A and Renova.

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